大学院保健学研究科
放射線技術科学領域
■ 講師：中原 岳久
- 学位
- 博士（理学）
- 職位
- 講師
- 所属
- 放射線生命科学分野
- 電話番号
- 0172-39-5935
- tnakahar
※アカウントの後に「@hirosaki-u.ac.jp」を加えてください。
学部
■ 専攻
放射線技術科学専攻
■ 研究テーマ
・放射線による生物への影響とその損傷の修復について
・大線量被ばく時の被ばく線量推測法について
■ キーワード
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業績
■ 著書
電磁場生命科学（京都大学学術出版会）共著
■ 学術論文
・1: Koyama S, Sakurai T, Nakahara T, Miyakoshi J.
・Extremely low frequency (ELF) magnetic fields enhance chemically induced formation of apurinic/apyrimidinic (AP) sites in A172 cells.
・Int J Radiat Biol. ;83(9):1-7. (2007)
・2: Miyakoshi J, Horiuchi E, Nakahara T, Sakurai T.
・Magnetic fields generated by an induction heating (IH) cook top do not cause genotoxicity in vitro.
・Bioelectromagnetics. ; 28(7):529-37. (2007)
・3: Liu Y, Nakahara T, Miyakoshi J, Hu DL, Nakane A, Abe Y.
・Nuclear accumulation and activation of nuclear factor kappaB after split-dose irradiation in LS174T cells.
・J Radiat Res (Tokyo). 48(1):13-20. (2007)
・4: Koyama S, Nakahara T, Sakurai T, Komatsubara Y, Isozumi Y, Miyakoshi J.
・Combined exposure of ELF magnetic fields and x-rays increased mutant yields compared with x-rays alone in pTN89 plasmids.
・J Radiat Res (Tokyo). ;46(2):257-64.(2005)
・5: Ding GR, Nakahara T, Hirose H, Koyama S, Takashima Y, Miyakoshi J.
・Extremely low frequency magnetic fields and the promotion of H2O2-induced cell death in HL-60 cells.
・Int J Radiat Biol. ;80(4):317-24.(2004)
・6: Koyama S, Nakahara T, Hirose H, Ding GR, Takashima Y, Isozumi Y, Miyakoshi J.
・ELF electromagnetic fields increase hydrogen peroxide (H2O2)-induced mutations in pTN89 plasmids.
・Mutat Res.:560(1):27-32.(2004)
・7: Hirose H, Nakahara T, Zhang QM, Yonei S, Miyakoshi J.
・Static magnetic field with a strong magnetic field gradient (41.7 T/m) induces c-Jun expression in HL-60 cells.
・In Vitro Cell Dev Biol Anim. ;39(8-9):348-52.(2003)
・8: Koyama S, Nakahara T, Wake K, Taki M, Isozumi Y, Miyakoshi J.
・Effects of high frequency electromagnetic fields on micronucleus formation in CHO-K1 cells.
・Mutat Res. ;541(1-2):81-9.(2003)
・9: Ding GR, Nakahara T, Miyakoshi J.
・Induction of kinetochore-positive and kinetochore-negative micronuclei in CHO cells by ELF magnetic fields and/or X-rays.
・Mutagenesis. ;18(5):439-43.(2003)
・10: Ding GR, Honda N, Nakahara T, Tian F, Yoshida M, Hirose H, Miyakoshi J.
・Radiosensitization by inhibition of IkappaB-alpha phosphorylation in human glioma cells.
・Radiat Res. ;160(2):232-7.(2003)
・11: Zhang QM, Tokiwa M, Doi T, Nakahara T, Chang PW, Nakamura N, Hori M, Miyakoshi J, Yonei S.
・Strong static magnetic field and the induction of mutations through elevated production of reactive oxygen species in Escherichia coli soxR.
・Int J Radiat Biol. ;79(4):281-6.(2003)
・12: Hirose H, Nakahara T, Miyakoshi J.
・Orientation of human glioblastoma cells embedded in type I collagen, caused by exposure to a 10 T static magnetic field.
・Neurosci Lett. ;338(1):88-90.(2003)
・13: Ding GR, Nakahara T, Miyakoshi J.
・Exposure to power frequency magnetic fields and X-rays induces GAP-43 gene expression in human glioma MO54 cells.
・Bioelectromagnetics. ;23(8):586-91.(2002)
・14: Nakahara T, Yaguchi H, Yoshida M, Miyakoshi J.
・Effects of exposure of CHO-K1 cells to a 10-T static magnetic field.
・Radiology. ;224(3):817-22.(2002)
・15: Tian F, Nakahara T, Wake K, Taki M, Miyakoshi J.
・Exposure to 2.45 GHz electromagnetic fields induces hsp70 at a high SAR of more than 20 W/kg but not at 5W/kg in human glioma MO54 cells.
・Int J Radiat Biol. ;78(5):433-40.(2002)
・16: Tian F, Nakahara T, Yoshida M, Honda N, Hirose H, Miyakoshi J.
・Exposure to power frequency magnetic fields suppresses X-ray-induced apoptosis transiently in Ku80-deficient xrs5 cells.
・Biochem Biophys Res Commun. ;292(2):355-61.(2002)
・17: Ding GR, Nakahara T, Tian FR, Guo Y, Miyakoshi J.
・Transient suppression of X-ray-induced apoptosis by exposure to power frequency magnetic fields in MCF-7 cells.
・Biochem Biophys Res Commun. ;286(5):953-7.(2001)
・18: Nakahara T, Zhang QM, Hashiguchi K, Yonei S.
・ Identification of proteins of Escherichia coli and Saccharomyces cerevisiae that specifically bind to C/C mismatches in DNA.
・Nucleic Acids Res. ;28(13):2551-6.(2000)
・19: Zhang QM, Ishikawa N, Nakahara T, Yonei S.
・Escherichia coli MutY protein has a guanine-DNA glycosylase that acts on 7,8-dihydro-8-oxoguanine:guanine mispair to prevent spontaneous G:C-->C:G transversions.
・Nucleic Acids Res. ;26(20):4669-75.(1998)
■ 総説/解説
・細胞曝露用超伝導磁場装置の開発と磁場効果の生命化学における応用（放射線生物研究、２００１年、第３６巻第２号：１７２－１８１）共著
・細胞や遺伝子は磁場に対してどのように応答するか？（化学と生物、２００１年、第３９巻第８号：４９６－４９８）共著
■ 社会活動
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■ 所属学会
・日本分子生物学会
・日本放射線影響学会
・日本医学放射線学会生物部会
・日本生体磁気学会
・Radiation Research Society
■ 備考
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