弘前大学医学部保健学科・大学院保健学研究科

■ 助教：宮崎　光江

学位

博士（医学）

職位

助教

所属

弘前大学大学院保健学研究科保健学専攻　医療生命科学領域　生体機能科学分野

電話番号

0172-39-5928

e-mail

miyazakm
※アカウントの後に「@hirosaki-u.ac.jp」を加えてください。

学部

■ 専攻

検査技術科学専攻

■ 研究テーマ

食欲調節因子ACBPの分泌機構の解明
脂肪前駆細胞分化抑制因子EID1の肝細胞への影響解析

■ キーワード

肥満、食欲調節、脂肪蓄積抑制、酵母遺伝学、分子生物学

業績

■ 著書

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■ 学術論文

• Comparison of the inhibitory effects of azole antifungals on cytochrome P450 3A4 genetic variants. 

  Yuki Yamaguchi, Takeshi Akiyoshi, Go Kawamura, Ayuko Imaoka, Mitsue Miyazaki, F Peter Guengerich, Katsunori Nakamura, Koujirou Yamamoto, Hisakazu Ohtani

  Drug metabolism and pharmacokinetics 38 100384 - 100384 2021年1月22日  
• EID1 suppresses lipid accumulation by inhibiting the expression of GPDH in 3T3-L1 preadipocytes. 

  Tomohiko Sato, Diana Vargas, Kakushin Miyazaki, Kaoru Uchida, Winda Ariyani, Mitsue Miyazaki, Junichi Okada, Fernando Lizcano, Noriyuki Koibuchi, Noriaki Shimokawa

  Journal of cellular physiology 2020年2月13日  
  
  L-Lactate dehydrogenase B may be a predictive marker for sensitivity to anti-EGFR monoclonal antibodies in colorectal cancer cell lines. 
• Ayumu Nagamine, Takuya Araki, Daisuke Nagano, Mitsue Miyazaki, Koujirou Yamamoto

  Oncology letters 17(5) 4710 - 4716 2019年5月  
  
  Potential Role of the Formation of Tunneling Nanotubes in HIV-1 Spread in Macrophages 
• Michihiro Hashimoto, Farzana Bhuyan, Masateru Hiyoshi, Osamu Noyori, Hesham Nasser, Mitsue Miyazaki, Tamio Saito, Yasumitsu Kondoh, Hiroyuki Osada, Shunsuke Kimura, Koji Hase, Hiroshi Ohno, Shinya Suzu

  JOURNAL OF IMMUNOLOGY 196(4) 1832 - 1841 2016年2月 
• Fibrocytes Differ from Macrophages but Can Be Infected with HIV-1 

  Michihiro Hashimoto, Hesham Nasser, Farzana Bhuyan, Nozomi Kuse, Yorifumi Satou, Shigeyoshi Harada, Kazuhisa Yoshimura, Jun-ichi Sakuragi, Kazuaki Monde, Yosuke Maeda, Sarah Welbourn, Klaus Strebel, Ekram W. Abd El-Wahab, Mitsue Miyazaki, Shinichiro Hattori, Nopporn Chutiwitoonchai, Masateru Hiyoshi, Shinichi Oka, Masafumi Takiguchi, Shinya Suzu

  JOURNAL OF IMMUNOLOGY 195(9) 4341 - 4350 2015年11月 
• Spongiacidin C, a pyrrole alkaloid from the marine sponge Stylissa massa, functions as a USP7 inhibitor 

  Michitaka Yamaguchi, Mitsue Miyazaki, Matthew P. Kodrasov, Henki Rotinsulu, Fitje Losung, Remy E.P. Mangindaan, Nicole J. De Voogd, Hideyoshi Yokosawa, Benjamin Nicholson, Sachiko Tsukamoto

  Bioorganic and Medicinal Chemistry Letters 23(13) 3884 - 3886 2013年7月1日  
• Himeic Acids E-G, New 4-Pyridone Derivatives from a Culture of Aspergillus sp. 

  Toshiyuki Kuwana, Mitsue Miyazaki, Hikaru Kato, Sachiko Tsukamoto

  CHEMICAL & PHARMACEUTICAL BULLETIN 61(1) 105 - 107 2013年1月 
• Mechanism-based inhibition profiles of erythromycin and clarithromycin with cytochrome P450 3A4 genetic variants 

  Takeshi Akiyoshi, Marie Ito, Saori Murase, Mitsue Miyazaki, F. Peter Guengerich, Katsunori Nakamura, Koujirou Yamamoto, Hisakazu Ohtani

  Drug Metabolism and Pharmacokinetics 28(5) 411 - 415 2013年 
• Hyrtioreticulins A-E, indole alkaloids inhibiting the ubiquitin-activating enzyme, from the marine sponge Hyrtios reticulatus 

  Rumi Yamanokuchi, Kumiko Imada, Mitsue Miyazaki, Hikaru Kato, Tadashi Watanabe, Masahiro Fujimuro, Yasushi Saeki, Sosuke Yoshinaga, Hiroaki Terasawa, Noriyuki Iwasaki, Henki Rotinsulu, Fitje Losung, Remy E. P. Mangindaan, Michio Namikoshi, Nicole J. de Voogd, Hideyoshi Yokosawa, Sachiko Tsukamoto

  BIOORGANIC & MEDICINAL CHEMISTRY 20(14) 4437 - 4442 2012年7月 
• Comparison of the Inhibitory Profiles of Itraconazole and Cimetidine in Cytochrome P450 3A4 Genetic Variants 

  Takeshi Akiyoshi, Takashi Saito, Saori Murase, Mitsue Miyazaki, Norie Murayama, Hiroshi Yamazaki, F. Peter Guengerich, Katsunori Nakamura, Koujirou Yamamoto, Hisakazu Ohtani

  DRUG METABOLISM AND DISPOSITION 39(4) 724 - 728 2011年4月 
• Defective Activity of Recombinant Cytochromes P450 3A4.2 and 3A4.16 in Oxidation of Midazolam, Nifedipine, and Testosterone 

  Mitsue Miyazaki, Katsunori Nakamura, Yukiyoshi Fujita, F. Peter Guengerich, Ryuya Horiuchi, Koujirou Yamamoto

  DRUG METABOLISM AND DISPOSITION 36(11) 2287 - 2291 2008年11月  
• Influence of atropine on the dose requirements of propofol in humans. 

  Takizawa E, Takizawa D, Al-Jahdari WS, Miyazaki M, Nakamura K, Yamamoto K, Horiuchi R, Hiraoka H

  Drug metabolism and pharmacokinetics 21(5) 384 - 388 2006年10月
• Abnormally high expression of proteasome activator-gamma in thyroid neoplasm 

  T Okamura, SI Taniguchi, T Ohkura, A Yoshida, H Shimizu, M Sakai, H Maeta, H Fukui, Y Ueta, Hisatome, I, C Shigemasa

  JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 88(3) 1374 - 1383 2003年3月

■ 総説/解説

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■ 社会活動

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■ 所属学会

日本分子生物学会
酵母遺伝学フォーラム
日本生理学会

■ 備考

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■ リンク

大学院保健学研究科